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Fosaprepitant inhibits the action of a chemical messenger in the brain that may cause vomiting, during the administration of cancer treatment drugs.

Product Description


Fosaprepitant is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). Fosaprepitant works by blocking one of the body’s natural substances (substance P/neurokinin 1) that causes vomiting.

This medication will not treat nausea or vomiting that has already started. Ask your doctor what you should do if you already have nausea or vomiting.

How to use fosaprepitant intravenous

Read the Patient Information Leaflet if available from your pharmacist before you start using fosaprepitant and each time you get treatment. If you have any questions, ask your doctor or pharmacist.

This medication is given by injection into a vein by a health care professional. It is given as directed by your doctor, usually 30 minutes before the start of chemotherapy. Your doctor may also direct you to take a form of this medication given by mouth (aprepitant) for the next 2 days. Follow your doctor’s instructions carefully. If you have any questions, ask your doctor or pharmacist.

Fosaprepitant may rarely cause severe allergic reactions (such as flushing, redness, or trouble breathing) while it is being given. Your doctor may decide to stop the infusion if this happens. Tell your healthcare professional right away if you have any of symptoms of a severe allergic reaction during your infusion. If the infusion is stopped, do not use fosaprepitant again.

Side Effects

See also How to Use section.Tiredness or hiccups may occur. If either of these effects lasts or gets worse, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.


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