LEUTERO

LEUTERO

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Leucovorin 50mg injection enters the cells as 5-methyl tetrahydrofolate and supplies the cofactor blocked by methotrexate. It stabilises the binding of 5-dUMP and thrymidylate synthetase, enhances flourouracil activity and neutralises the effects of folic acid antagonists such as methotrexate but increases those of 5-fluorouracil.

Product Description

Uses

Leucovorin 50mg injection is used in the treatment of ovarian cancer, blood cancer, hemorrhagic cystitis and methotrexate toxicity

How it works

Leucovorin 50mg injection enters the cells as 5-methyl tetrahydrofolate and supplies the cofactor blocked by methotrexate. It stabilises the binding of 5-dUMP and thrymidylate synthetase, enhances flourouracil activity and neutralises the effects of folic acid antagonists such as methotrexate but increases those of 5-fluorouracil.

Common side effects

Nausea, Vomiting, Diarrhoea, Mucosal inflammation

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