Why is this medication prescribed?
Sofosbuvir is used along with ribavirin (Copegus, Rebetol) and sometimes another medication (peginterferon alfa [Pegasys] to treat chronic hepatitis C (an ongoing viral infection that damages the liver). Sofosbuvir is also used along with ribavirin (Copegus, Rebetol) in people with liver cancer and hepatitis C infection who are waiting for a liver transplant to treat hepatitis C infection and to decrease the risk of reinfection after the transplant. Sofosbuvir is in a class of antiviral medications called nucleotide polymerase inhibitors. It works by decreasing the amount of hepatitis C virus (HCV) in the body. Sofosbuvir may not prevent the spread of hepatitis C to other people.
How should this medicine be used?
Sofosbuvir comes as a tablet to take by mouth. It is usually taken with or without food once a day. Take sofosbuvir at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sofosbuvir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Continue to take sofosbuvir even if you feel well. Sofosbuvir must be taken in combination with peginterferon alfa and ribavirin or in combination with ribavirin alone. If sofosbuvir is taken in combination with peginterferon alfa and ribavirin, it is usually taken for 12 weeks. If sofosbuvir is taken in combination with ribavirin alone, it is usually taken for 12 or 24 weeks. If you have liver cancer and are waiting for a liver transplant, you will take sofosbuvir with ribavirin for up to 48 weeks or until you have a liver transplant. The length of your treatment depends on your condition, how well you respond to the medication, and whether you experience severe side effects. Do not stop taking sofosbuvir, peginterferon alfa, or ribavirin, unless told to do so by your doctor.
Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.