SOFOVIR 400MG TABLETS:
Sofovir 400mg Tablet (Sofosbuvir) is AN antiviral medication recycled in the treatment of chronic viral hepatitis C infection. It’s utilized in patients with liver disease and viral hepatitis infection WHO square measure going to have a liver transplantation. This medication minimizes the prospect of a repetition of the infection once the transplantation. Sofovir four hundred mg pill isn’t suggested to be used in patients with a better-known history of viral hepatitis infection.
SOFOVIR-C — USAGE INSTRUCTIONS:
The active ingredient is sofosbuvir. Inhibitor of RNA-polymerase NS5B, which suppresses replication (reproduction) of the virus of hepatitis C. the new drug’s direct antiviral action.
The drug acts directly on the hepatitis C Sofosbuvir blocks the main stages in the reproduction of the virus. Used for the treatment of patients with the first, second, third and fourth genotype.
Indications for use:
A medicine used for the treatment of chronic hepatitis C in adults in combination with other antiviral drugs.
Method of application:
The drug is taken once a day in a dosage of 400 mg (1 tablet). The pill is better not to chew, as it has intense bitter taste. The medication is best taken during meals, drinking plenty of water. Take the drug daily, at the same time.
In General, the drug is well tolerated and has no pronounced side effects. The most common of these is fatigue, headache, and nausea. The severity of adverse effects is increased with combination therapy with interferon and other antiviral drugs.
Starting therapy with sofosbuvir, watch out for their health. Report to the attending physician of any abnormalities or adverse events.
The drug should not be taken:
Children and adolescents under 18 years of age;
In the period of breastfeeding;
In case of hypersensitivity to the active substance.
These groups of patients should not undergo therapy with sofosbuvir, as clinical trials for these groups was conducted.
Women of reproductive age should take the drug with caution because at the moment the effect of sofosbuvir on the reproductive function is still unclear.
Elderly patients and patients with renal and hepatic insufficiency should be treated only under careful medical supervision. For mild renal and hepatic insufficiency, a dosage adjustment is not necessary.
Interaction with other medicinal products:
The drug is used in combination with other antiviral drugs only when the efficiency exceeds possible complications. The drug should not be combined with Boceprevir or Telaprevir.
At a therapeutic dose of 400 mg per day the drug does not affect the duration of the QT interval and cause of disorders in the cardiovascular system.
Treatment should be under careful supervision of a doctor;
The drug is recommended to take in combination with other antiviral drugs;
Monotherapy with sofosbuvir is not recommended;
The recommended dose for adults is 400 mg daily (1 tablet) while eating;
Do not reduce the daily dose;
The medication has an unpleasant bitter taste, so the drug is best not to chew and not to divide into parts;
If within two hours after taking the medicine happened vomiting – take an extra tablet;
If the vomiting happened after two hours of additional tablet is not required;
When the drug did not take place for any reason, drink immediately missed tablet. The next time you can take the pill at the usual time;
During treatment, refrain from activities that require a speed of reaction and attention.
The form of issue:
Oval tablets in a dosage of 400 mg. of 7 pills in the pack.
Keep the medication in a dry, protected from sunlight and reach of children. Date of manufacture and shelf life indicated on the package. Do not take this medicine after the expiry date printed on the package. Keep the preparation at a temperature from 15 to 30° C.
One tablet contains 400 mg sofosbuvir.
International name – Sofovir-C.
Manufacturer: Pharmaceutical company Hetero (India) Ltd.