Sofosbuvir 400mg

The drug from hepatitis C “Sofosbuvir 400mg tablets”: reviews, instructions for use

The drug Sofosbuvir 400mg tablets with the trade name “Sovaldi” allows to completely cure hepatitis C, while a positive result is achieved quickly enough, which is confirmed by clinical studies. The medicinal product “Sofosbuvir” is treated with a chronic form of hepatitis C. Complex therapy with the use of this drug and other medications are prescribed for adult patients. The drug also treats patients with HIV and co-infections.

The active component of the tablets is Sofosbuvir. They are coated and contain 400 mg of the basic substance. The package contains 28 tablets.

The properties of the drug “Sofosbuvir tablets 400mg”

The drug has a depressing effect on the NS5B RNA polymerase. As a result of its influence on the body, the process of replication of the virus is inhibited, which is the causative agent of hepatitis C.

Where to buy Sofosbuvir online at an affordable price

The most useful information on how you can safely get your “course of recovery” is posted on topical websites. The largest and most socially significant resource is HEPSAFE.COM – speaking hepatitis forum “at the stop,” which was founded in 2000. As a rule, on serious portals, all information is carefully checked by the administration and has a public evaluation.

If you do not take into account the forums, then one of the most interesting proposals that we managed to find on the Internet, called HEPSAFE ACCESS PROGRAM. More information about HEPSAFE services is available on the official website of the program.

Indications for use of the drug

The drug “Sofosbuvir 400mg” is prescribed for patients with hepatitis C, when the disease has passed into a chronic form. A combined approach is used for the effectiveness of treatment. It is possible to use medicament in cases when the patient has HIV in addition to hepatitis.

Contraindications to taking the drug “Sofosbuvir 400mg tablets

The drug is not used for hypersensitivity to substances that are present in its composition. Despite the fact that the drug does not affect fertility, it is rarely prescribed to women in their reproductive years. The use of the drug during pregnancy and breastfeeding is not recommended, as it can be harmful to the child.

When pregnancy occurs, the combination of sofosbuvir 400mg tablets with such drugs as Interferon alfa and Ribavirin may have a negative effect on its course. For this reason, during the period of treatment, the child’s bearing is undesirable. The experiments, during which the drug “Sofosbuvir tablets” was tested in animals, showed that this drug has a slightly negative impact on the offspring. Before you start taking it, you should carefully study the instructions for the drug and consult with a specialist.

A dosage of the drug “Sofosbuvir 400mg tablets”

Treatment of “Sofosbuvir 400mg tablets” hepatitis C of a chronic form can be performed only by those specialists who have relevant experience. Monotherapy is not performed; the drug is always combined with other drugs. Often adults are recommended to take 400 mg (1 tablet) a day. The tablet is drunk while eating.


Therapy with Sofosbuvir from hepatitis C can last up to six months. Especially often such a need arises when there are some negative factors. The dose of the drug is selected taking into account the weight of the patient. Combined treatment for hepatitis C: genotypes 3-6 – to the main drug add “Interferon alfa” and Ribavirin (treatment takes more than three months); genotypes 1, 4-6 – additionally apply “Interferon alfa” and “Ribavirin” for three months or only “Ribavirin” for six months (the second option is realized only if it is impossible to use the first method); genotype 2 – the drug is combined with “Ribavirin”, recovery usually comes after three months of use of drugs. If it is necessary to transplant the liver to a person who has hepatitis C, prescribe “Sofosbuvir” together with “Ribavirin” before it is administered. During the period of therapy with Sofosbuvir, the scheme of treatment of patients with coexisting HIV and hepatitis can be used the same. When side effects occur due to the combined use of a drug with Interferon alfa, accompanied by serious disorders, Interferon refuses or reduces the previously established dosage. If Ribavirin is to blame for the development of serious side effects, its dose is also reduced or canceled by this medication. Such decisions are made by the attending physician. Later, when the patient’s condition is normal, you can try to resume taking medications.

Drug Interactions

Complex therapy using Sofosbuvir means that reviews can be performed if the possible risks are exceeded. Experts do not advise to be treated simultaneously with this drug and “Boceprevir” or “Telaprevir”. The same applies to the combination of the drug with medications, which are considered inducers of high-potency glycoproteins. To drugs with such properties belong to “Phonation”, “Carbamazepine”. Of these funds, it is possible to isolate St. John’s wort and “Rifamycin”. The possibility of combining certain medicines is established by the doctor.

Leave a Reply

Your email address will not be published. Required fields are marked *